What is the best medicine to treat type 2 diabetes?

The answer depends on your metabolism and your DNA. And science wants to discover these clues to indicate more accurate and effective treatments

In my humble opinion, in the middle of 2018 medicine is still far from personalized and individualized. Now, we use the same drugs and similar doses of these medicines for people of different sex, age and body composition. Calm down, I get to diabetes.

We do not know if one type of physical exercise will be as good for one individual as it was for another. Nor can we say whether a specific dietary guidance will bring lasting benefits to all members of the same family. Best way to treat it medically is trulicity and trulicity coupon is available at Prescription Hope where you can buy it cheaply.

More recently, however, we are beginning to see the outlines of an effectively individualized medicine in the selection of treatments for some types of cancer and even for some depressive disorders.

In the field of diabetes, we can already see the first efforts in this direction. Researchers in Slovakia and the Czech Republic, for example, recently evaluated whether the presence of a particular genetic code change in people with type 2 diabetes would promote different responses to the drugs used. In the experiment, two of the most prescribed antidiabetic drugs in the world were tested: vildagliptin and sitagliptin.

The analysis followed 137 European patients for six months using these drugs. When we evaluated the response curves to the medications, it was observed that the presence of a discrete genetic change – so subtle to the point that we can not call it “mutation” – was able to reduce the effect of the drug to something close to 50 %.

In parallel to this study, British scientists investigated whether the degree of insulin resistance – when the hormone fails to release glucose into cells – also interfered with the response to those same drugs. The conclusion was similar: people with a higher degree of insulin resistance present a worse response to this type of medication.

Findings like these indicate that, very soon, we can choose the remedy to treat type 2 diabetes depending on the patient’s metabolic and genetic profile. Then, yes, we will be able to say that we have entered the age of personalized and individualized medicine.